Convergent and stereoselective synthesis of trisubstituted E-alkenyl bromides and iodides via beta-oxido phosphonium ylides.
β-Oxido phosphonium ylides, generated in situ from aldehydes and Wittig reagents [alkylidene(triphenyl)phosphoranes, other than ethylidene(triphenyl)phosphorane], react readily with electrophilic halogen sources to form predominantly or exclusively E-bromo- or iodosubstituted alkenes. The stereochem...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2008
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