Detection of microglial activation in an acute model of neuroinflammation using PET and radiotracers 11C-(R)-PK11195 and 18F-GE-180.

UNLABELLED: It remains unclear how different translocator protein (TSPO) ligands reflect the spatial extent of astrocyte or microglial activation in various neuroinflammatory conditions. Here, we use a reproducible lipopolysaccharide (LPS)-induced model of acute central nervous system inflammation t...

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Bibliographic Details
Main Authors: Dickens, A, Vainio, S, Marjamäki, P, Johansson, J, Lehtiniemi, P, Rokka, J, Rinne, J, Solin, O, Haaparanta-Solin, M, Jones, P, Trigg, W, Anthony, D, Airas, L
Format: Journal article
Language:English
Published: 2014