The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA.
The ADAR RNA-editing enzymes deaminate adenosine bases to inosines in cellular RNAs. Aberrant interferon expression occurs in patients in whom ADAR1 mutations cause Aicardi-Goutières syndrome (AGS) or dystonia arising from striatal neurodegeneration. Adar1 mutant mouse embryos show aberrant interfer...
Egile Nagusiak: | Mannion, N, Greenwood, S, Young, R, Cox, S, Brindle, J, Read, D, Nellåker, C, Vesely, C, Ponting, C, McLaughlin, P, Jantsch, M, Dorin, J, Adams, I, Scadden, A, Ohman, M, Keegan, L, O'Connell, M |
---|---|
Formatua: | Journal article |
Hizkuntza: | English |
Argitaratua: |
Elsevier
2014
|
Antzeko izenburuak
-
Nucleocytoplasmic distribution of human RNA-editing enzyme ADAR1 is modulated by double-stranded RNA-binding domains, a leucine-rich export signal, and a putative dimerization domain.
nork: Strehblow, A, et al.
Argitaratua: (2002) -
Core-binding factor fusion downregulation of ADAR2 RNA editing contributes to AML leukemogenesis
nork: Guo, Mingrui, et al.
Argitaratua: (2023) -
Molecular characterization of human double-stranded RNA specific adenosine deaminases (ADARs)
nork: Ong, Zi Xin
Argitaratua: (2016) -
RNA aptamers binding the double-stranded RNA-binding domain.
nork: Hallegger, M, et al.
Argitaratua: (2006) -
Induction of z-conformation in ribosomal RNA by Z-DNA binding domain Zα of the human double-stranded RNA deaminase I (ADAR1)
nork: Zhao, Jing
Argitaratua: (2012)