DNA-structured mathematical model of cell-cycle progression in cyclic hypoxia

New experimental data have shown how the periodic exposure of cells to low oxygen levels (i.e., cyclic hypoxia) impacts their progress through the cell-cycle. Cyclic hypoxia has been detected in tumours and linked to poor prognosis and treatment failure. While fluctuating oxygen environments can be...

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Bibliographic Details
Main Authors: Celora, G, Bader, S, Hammond, EM, Maini, P, Pitt-Francis, J, Byrne, H
Format: Journal article
Language:English
Published: Elsevier 2022