Spliceosome-mediated decay (SMD) regulates expression of nonintronic genes in budding yeast.

We uncovered a novel role for the spliceosome in regulating mRNA expression levels that involves splicing coupled to RNA decay, which we refer to as spliceosome-mediated decay (SMD). Our transcriptome-wide studies identified numerous transcripts that are not known to have introns but are spliced by...

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Detalhes bibliográficos
Principais autores: Volanakis, A, Passoni, M, Hector, R, Shah, S, Kilchert, C, Granneman, S, Vasiljeva, L
Formato: Journal article
Idioma:English
Publicado em: 2013