Cyclin-Dependent Kinase 12 (CDK12), Human Kinase Domain; A Target Enabling Package

A description of the materials and methods is included within the TEP datasheet. Cyclin-dependent kinase 12 (CDK12) phosphorylates RNA Pol II C-terminal domain (CTD) to promote transcriptional elongation of large DNA damage response genes. CDK12 is frequently mutated or amplified in cancer and its l...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Άλλοι συγγραφείς: Bullock, A
Μορφή: Dataset
Έκδοση: University of Oxford 2018
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