Cyclin-Dependent Kinase 12 (CDK12), Human Kinase Domain; A Target Enabling Package

Cyclin-Dependent Kinase 12 (CDK12), Human Kinase Domain; A Target Enabling Package

A description of the materials and methods is included within the TEP datasheet. Cyclin-dependent kinase 12 (CDK12) phosphorylates RNA Pol II C-terminal domain (CTD) to promote transcriptional elongation of large DNA damage response genes. CDK12 is frequently mutated or amplified in cancer and its l...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Άλλοι συγγραφείς:	Bullock, A
Μορφή:	Dataset
Έκδοση:	University of Oxford 2018
Θέματα:	Chemical Biology Structural Genomics Drug Discovery

Παρόμοια τεκμήρια

Cyclin-dependent kinase 12 (CDK12), human kinase domain; a Target Enabling Package
ανά: Dixon-Clarke, S
Έκδοση: (2018)

Cyclin-Dependent Kinase 12 (CDK12), human kinase domain; A Target Enabling Package
Έκδοση: (2018)

LIM domain kinase 1 (LIMK1), human kinase domain; A Target Enabling Package
ανά: Mathea, S
Έκδοση: (2018)

LIM Domain Kinase 1 (LIMK1), Human Kinase Domain; A Target Enabling Package
ανά: Bullock, A
Έκδοση: (2018)

LIM Domain Kinase 1 (LIMK1), human kinase domain; A Target Enabling Package
ανά: Mathea, S
Έκδοση: (2018)

With No Lysine Kinase 3 (WNK3); A Target Enabling Package
ανά: Bullock, A
Έκδοση: (2018)

With no lysine kinase 3 (WNK3); A Target Enabling Package
ανά: Pinkas, D
Έκδοση: (2018)

With No Lysine Kinase 3 (WNK3); A Target Enabling Package
ανά: Pinkas, D
Έκδοση: (2018)

Pleckstrin Homology Domain Interacting Protein (PHIP); A Target Enabling Package
ανά: Cox, O
Έκδοση: (2018)

Pleckstrin Homology Domain Interacting Protein (PHIP); A Target Enabling Package
ανά: Cox, O
Έκδοση: (2018)

Pleckstrin Homology Domain Interacting Protein (PHIP); A Target Enabling Package
ανά: Brennan, P
Έκδοση: (2018)

Human RECQL5 Helicase; A Target Enabling Package
ανά: Gileadi, O
Έκδοση: (2018)

Human RECQL5 Helicase; A Target Enabling Package
ανά: Newman, J
Έκδοση: (2018)

Human RECQL5 Helicase; A Target Enabling Package
ανά: Newman, J
Έκδοση: (2018)

Human alpha-aminoadipic semialdehyde synthase (AASS); A Target Enabling Package
Έκδοση: (2018)

Human alpha-aminoadipic semialdehyde synthase (AASS); A Target Enabling Package
ανά: Kopec, J
Έκδοση: (2018)

Human alpha-aminoadipic semialdehyde synthase (AASS); A Target Enabling Package
ανά: Yue, W
Έκδοση: (2018)

Lysine Demethylase JMJD2D (KDM4D); A Targeting Enabling Package
ανά: Brennan, P
Έκδοση: (2018)

Lysine Demethylase JMJD1B (KDM3B); A Target Enabling Package
ανά: Brennan, P
Έκδοση: (2018)

Lysine Demethylase JMJD2D (KDM4D); A Targeting Enabling Package
ανά: Savitsky, P
Έκδοση: (2018)

Lysine Demethylase JMJD1B (KDM3B); A Target Enabling Package
ανά: Brennan, P
Έκδοση: (2018)

Lysine Demethylase JMJD2D (KDM4D); A Targeting Enabling Package
ανά: Brennan, P
Έκδοση: (2018)

Lysine Demethylase JMJD1B (KDM3B); A Target Enabling Package
ανά: Savitsky, P
Έκδοση: (2018)

Dolichyl-Phosphate Alpha-N-Acetyl Glucosaminyl Transferase (DPAGT1); A Target Enabling Package
ανά: Carpenter, E
Έκδοση: (2018)

Dolichyl-Phosphate Alpha-N-Acetyl Glucosaminyl Transferase (DPAGT1); A Target Enabling Package
ανά: Chu, A
Έκδοση: (2018)

Dolichyl-Phosphate Alpha-N-Acetyl Glucosaminyl Transferase (DPAGT1); A Target Enabling Package
ανά: Dong, Y
Έκδοση: (2018)

Human DNA Cross-Link Repair 1A (DCLRE1A, SNM1A); A Target Enabling Package
ανά: Newman, J
Έκδοση: (2018)

Human DNA Cross-Link Repair 1A (DCLRE1A, SNM1A); A Target Enabling Package
ανά: Gileadi, O
Έκδοση: (2018)

Human DNA Cross-Link Repair 1A (DCLRE1A, SNM1A); A Target Enabling Package
ανά: Newman, J
Έκδοση: (2018)

Meiotic regulation of cyclin-dependent kinases
ανά: Miller, Matthew P., Ph. D. (Matthew Paul). Massachusetts Institute of Technology
Έκδοση: (2013)

Identification and Functional Characterisation of CRK12:CYC9, a Novel Cyclin-Dependent Kinase (CDK)-Cyclin Complex in Trypanosoma brucei.
ανά: Séverine Monnerat, κ.ά.
Έκδοση: (2013-01-01)

Mapping kinase domain resistance mechanisms for the MET receptor tyrosine kinase via deep mutational scanning
ανά: Gabriella O Estevam, κ.ά.
Έκδοση: (2025-02-01)

Cyclin-dependent kinase (CDK) 4/6 inhibitors in oncology
ανά: Karamitrousis Evangelos, κ.ά.
Έκδοση: (2020-04-01)

Cyclin-dependent kinases and CDK inhibitors in virus-associated cancers
ανά: Shaian Tavakolian, κ.ά.
Έκδοση: (2020-05-01)

Cyclin-Dependent Kinase regulation and function during meiosis
ανά: Carlile, Thomas M. (Thomas Marshal), Jr
Έκδοση: (2010)

Cyclin‐dependent kinase 12‐mediated super‐enhancers as promising targets in cancer therapy
ανά: Fuda Xie, κ.ά.
Έκδοση: (2022-12-01)

Functional characterization of the cyclin-dependent kinase inhibitor p21 by gene targeting in the mouse
ανά: Brugarolas, James (James Burfau), 1969-
Έκδοση: (2009)

Cyclin-dependent kinase 5 (CDK5) regulates the circadian clock
ανά: Andrea Brenna, κ.ά.
Έκδοση: (2019-11-01)

The Role of Pharmacokinetics and Pharmacodynamics in Early Drug Development with reference to the Cyclin-dependent Kinase (Cdk) Inhibitor - Roscovitine
ανά: Moustapha Hassan, κ.ά.
Έκδοση: (2011-08-01)

Cyclin K goes with Cdk12 and Cdk13
ανά: Kohoutek Jiri, κ.ά.
Έκδοση: (2012-04-01)