Cyclin-Dependent Kinase 12 (CDK12), Human Kinase Domain; A Target Enabling Package

Cyclin-Dependent Kinase 12 (CDK12), Human Kinase Domain; A Target Enabling Package

A description of the materials and methods is included within the TEP datasheet. Cyclin-dependent kinase 12 (CDK12) phosphorylates RNA Pol II C-terminal domain (CTD) to promote transcriptional elongation of large DNA damage response genes. CDK12 is frequently mutated or amplified in cancer and its l...

Deskribapen osoa

Xehetasun bibliografikoak
Beste egile batzuk:	Bullock, A
Formatua:	Dataset
Argitaratua:	University of Oxford 2018
Gaiak:	Chemical Biology Structural Genomics Drug Discovery

Antzeko izenburuak

Cyclin-dependent kinase 12 (CDK12), human kinase domain; a Target Enabling Package
nork: Dixon-Clarke, S
Argitaratua: (2018)

Cyclin-Dependent Kinase 12 (CDK12), human kinase domain; A Target Enabling Package
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LIM domain kinase 1 (LIMK1), human kinase domain; A Target Enabling Package
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LIM Domain Kinase 1 (LIMK1), Human Kinase Domain; A Target Enabling Package
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LIM Domain Kinase 1 (LIMK1), human kinase domain; A Target Enabling Package
nork: Mathea, S
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With No Lysine Kinase 3 (WNK3); A Target Enabling Package
nork: Bullock, A
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With no lysine kinase 3 (WNK3); A Target Enabling Package
nork: Pinkas, D
Argitaratua: (2018)

With No Lysine Kinase 3 (WNK3); A Target Enabling Package
nork: Pinkas, D
Argitaratua: (2018)

Pleckstrin Homology Domain Interacting Protein (PHIP); A Target Enabling Package
nork: Cox, O
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Pleckstrin Homology Domain Interacting Protein (PHIP); A Target Enabling Package
nork: Cox, O
Argitaratua: (2018)

Pleckstrin Homology Domain Interacting Protein (PHIP); A Target Enabling Package
nork: Brennan, P
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Human RECQL5 Helicase; A Target Enabling Package
nork: Gileadi, O
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Human RECQL5 Helicase; A Target Enabling Package
nork: Newman, J
Argitaratua: (2018)

Human RECQL5 Helicase; A Target Enabling Package
nork: Newman, J
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Human alpha-aminoadipic semialdehyde synthase (AASS); A Target Enabling Package
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Human alpha-aminoadipic semialdehyde synthase (AASS); A Target Enabling Package
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Human alpha-aminoadipic semialdehyde synthase (AASS); A Target Enabling Package
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Lysine Demethylase JMJD2D (KDM4D); A Targeting Enabling Package
nork: Brennan, P
Argitaratua: (2018)

Lysine Demethylase JMJD1B (KDM3B); A Target Enabling Package
nork: Brennan, P
Argitaratua: (2018)

Lysine Demethylase JMJD2D (KDM4D); A Targeting Enabling Package
nork: Savitsky, P
Argitaratua: (2018)

Lysine Demethylase JMJD1B (KDM3B); A Target Enabling Package
nork: Brennan, P
Argitaratua: (2018)

Lysine Demethylase JMJD2D (KDM4D); A Targeting Enabling Package
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Argitaratua: (2018)

Lysine Demethylase JMJD1B (KDM3B); A Target Enabling Package
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Argitaratua: (2018)

Dolichyl-Phosphate Alpha-N-Acetyl Glucosaminyl Transferase (DPAGT1); A Target Enabling Package
nork: Carpenter, E
Argitaratua: (2018)

Dolichyl-Phosphate Alpha-N-Acetyl Glucosaminyl Transferase (DPAGT1); A Target Enabling Package
nork: Chu, A
Argitaratua: (2018)

Dolichyl-Phosphate Alpha-N-Acetyl Glucosaminyl Transferase (DPAGT1); A Target Enabling Package
nork: Dong, Y
Argitaratua: (2018)

Human DNA Cross-Link Repair 1A (DCLRE1A, SNM1A); A Target Enabling Package
nork: Newman, J
Argitaratua: (2018)

Human DNA Cross-Link Repair 1A (DCLRE1A, SNM1A); A Target Enabling Package
nork: Gileadi, O
Argitaratua: (2018)

Human DNA Cross-Link Repair 1A (DCLRE1A, SNM1A); A Target Enabling Package
nork: Newman, J
Argitaratua: (2018)

Meiotic regulation of cyclin-dependent kinases
nork: Miller, Matthew P., Ph. D. (Matthew Paul). Massachusetts Institute of Technology
Argitaratua: (2013)

Identification and Functional Characterisation of CRK12:CYC9, a Novel Cyclin-Dependent Kinase (CDK)-Cyclin Complex in Trypanosoma brucei.
nork: Séverine Monnerat, et al.
Argitaratua: (2013-01-01)

Mapping kinase domain resistance mechanisms for the MET receptor tyrosine kinase via deep mutational scanning
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Cyclin-dependent kinase (CDK) 4/6 inhibitors in oncology
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Argitaratua: (2020-04-01)

Cyclin-Dependent Kinase regulation and function during meiosis
nork: Carlile, Thomas M. (Thomas Marshal), Jr
Argitaratua: (2010)

Cyclin‐dependent kinase 12‐mediated super‐enhancers as promising targets in cancer therapy
nork: Fuda Xie, et al.
Argitaratua: (2022-12-01)

Cyclin-dependent kinase 5 (CDK5) regulates the circadian clock
nork: Andrea Brenna, et al.
Argitaratua: (2019-11-01)

Functional characterization of the cyclin-dependent kinase inhibitor p21 by gene targeting in the mouse
nork: Brugarolas, James (James Burfau), 1969-
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Cyclin K goes with Cdk12 and Cdk13
nork: Kohoutek Jiri, et al.
Argitaratua: (2012-04-01)

Cyclin A and Cks1 promote kinase consensus switching to non-proline-directed CDK1 phosphorylation
nork: Aymen al-Rawi, et al.
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The awakening of the CDK10/Cyclin M protein kinase
nork: Gamble, Carly, et al.
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