Cyclin-Dependent Kinase 12 (CDK12), Human Kinase Domain; A Target Enabling Package

Cyclin-Dependent Kinase 12 (CDK12), Human Kinase Domain; A Target Enabling Package

A description of the materials and methods is included within the TEP datasheet. Cyclin-dependent kinase 12 (CDK12) phosphorylates RNA Pol II C-terminal domain (CTD) to promote transcriptional elongation of large DNA damage response genes. CDK12 is frequently mutated or amplified in cancer and its l...

पूर्ण विवरण

ग्रंथसूची विवरण
अन्य लेखक:	Bullock, A
स्वरूप:	Dataset
प्रकाशित:	University of Oxford 2018
विषय:	Chemical Biology Structural Genomics Drug Discovery

समान संसाधन

Cyclin-dependent kinase 12 (CDK12), human kinase domain; a Target Enabling Package
द्वारा: Dixon-Clarke, S
प्रकाशित: (2018)

Cyclin-Dependent Kinase 12 (CDK12), human kinase domain; A Target Enabling Package
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LIM domain kinase 1 (LIMK1), human kinase domain; A Target Enabling Package
द्वारा: Mathea, S
प्रकाशित: (2018)

LIM Domain Kinase 1 (LIMK1), Human Kinase Domain; A Target Enabling Package
द्वारा: Bullock, A
प्रकाशित: (2018)

LIM Domain Kinase 1 (LIMK1), human kinase domain; A Target Enabling Package
द्वारा: Mathea, S
प्रकाशित: (2018)

With No Lysine Kinase 3 (WNK3); A Target Enabling Package
द्वारा: Bullock, A
प्रकाशित: (2018)

With no lysine kinase 3 (WNK3); A Target Enabling Package
द्वारा: Pinkas, D
प्रकाशित: (2018)

With No Lysine Kinase 3 (WNK3); A Target Enabling Package
द्वारा: Pinkas, D
प्रकाशित: (2018)

Pleckstrin Homology Domain Interacting Protein (PHIP); A Target Enabling Package
द्वारा: Cox, O
प्रकाशित: (2018)

Pleckstrin Homology Domain Interacting Protein (PHIP); A Target Enabling Package
द्वारा: Cox, O
प्रकाशित: (2018)

Pleckstrin Homology Domain Interacting Protein (PHIP); A Target Enabling Package
द्वारा: Brennan, P
प्रकाशित: (2018)

Human RECQL5 Helicase; A Target Enabling Package
द्वारा: Gileadi, O
प्रकाशित: (2018)

Human RECQL5 Helicase; A Target Enabling Package
द्वारा: Newman, J
प्रकाशित: (2018)

Human RECQL5 Helicase; A Target Enabling Package
द्वारा: Newman, J
प्रकाशित: (2018)

Human alpha-aminoadipic semialdehyde synthase (AASS); A Target Enabling Package
प्रकाशित: (2018)

Human alpha-aminoadipic semialdehyde synthase (AASS); A Target Enabling Package
द्वारा: Kopec, J
प्रकाशित: (2018)

Human alpha-aminoadipic semialdehyde synthase (AASS); A Target Enabling Package
द्वारा: Yue, W
प्रकाशित: (2018)

Lysine Demethylase JMJD2D (KDM4D); A Targeting Enabling Package
द्वारा: Brennan, P
प्रकाशित: (2018)

Lysine Demethylase JMJD1B (KDM3B); A Target Enabling Package
द्वारा: Brennan, P
प्रकाशित: (2018)

Lysine Demethylase JMJD2D (KDM4D); A Targeting Enabling Package
द्वारा: Savitsky, P
प्रकाशित: (2018)

Lysine Demethylase JMJD1B (KDM3B); A Target Enabling Package
द्वारा: Brennan, P
प्रकाशित: (2018)

Lysine Demethylase JMJD2D (KDM4D); A Targeting Enabling Package
द्वारा: Brennan, P
प्रकाशित: (2018)

Lysine Demethylase JMJD1B (KDM3B); A Target Enabling Package
द्वारा: Savitsky, P
प्रकाशित: (2018)

Dolichyl-Phosphate Alpha-N-Acetyl Glucosaminyl Transferase (DPAGT1); A Target Enabling Package
द्वारा: Carpenter, E
प्रकाशित: (2018)

Dolichyl-Phosphate Alpha-N-Acetyl Glucosaminyl Transferase (DPAGT1); A Target Enabling Package
द्वारा: Chu, A
प्रकाशित: (2018)

Dolichyl-Phosphate Alpha-N-Acetyl Glucosaminyl Transferase (DPAGT1); A Target Enabling Package
द्वारा: Dong, Y
प्रकाशित: (2018)

Human DNA Cross-Link Repair 1A (DCLRE1A, SNM1A); A Target Enabling Package
द्वारा: Newman, J
प्रकाशित: (2018)

Human DNA Cross-Link Repair 1A (DCLRE1A, SNM1A); A Target Enabling Package
द्वारा: Gileadi, O
प्रकाशित: (2018)

Human DNA Cross-Link Repair 1A (DCLRE1A, SNM1A); A Target Enabling Package
द्वारा: Newman, J
प्रकाशित: (2018)

Meiotic regulation of cyclin-dependent kinases
द्वारा: Miller, Matthew P., Ph. D. (Matthew Paul). Massachusetts Institute of Technology
प्रकाशित: (2013)

Identification and Functional Characterisation of CRK12:CYC9, a Novel Cyclin-Dependent Kinase (CDK)-Cyclin Complex in Trypanosoma brucei.
द्वारा: Séverine Monnerat, और अन्य
प्रकाशित: (2013-01-01)

Mapping kinase domain resistance mechanisms for the MET receptor tyrosine kinase via deep mutational scanning
द्वारा: Gabriella O Estevam, और अन्य
प्रकाशित: (2025-02-01)

Cyclin-dependent kinase (CDK) 4/6 inhibitors in oncology
द्वारा: Karamitrousis Evangelos, और अन्य
प्रकाशित: (2020-04-01)

Cyclin-dependent kinases and CDK inhibitors in virus-associated cancers
द्वारा: Shaian Tavakolian, और अन्य
प्रकाशित: (2020-05-01)

Cyclin-Dependent Kinase regulation and function during meiosis
द्वारा: Carlile, Thomas M. (Thomas Marshal), Jr
प्रकाशित: (2010)

Cyclin‐dependent kinase 12‐mediated super‐enhancers as promising targets in cancer therapy
द्वारा: Fuda Xie, और अन्य
प्रकाशित: (2022-12-01)

Functional characterization of the cyclin-dependent kinase inhibitor p21 by gene targeting in the mouse
द्वारा: Brugarolas, James (James Burfau), 1969-
प्रकाशित: (2009)

Cyclin-dependent kinase 5 (CDK5) regulates the circadian clock
द्वारा: Andrea Brenna, और अन्य
प्रकाशित: (2019-11-01)

The Role of Pharmacokinetics and Pharmacodynamics in Early Drug Development with reference to the Cyclin-dependent Kinase (Cdk) Inhibitor - Roscovitine
द्वारा: Moustapha Hassan, और अन्य
प्रकाशित: (2011-08-01)

Cyclin K goes with Cdk12 and Cdk13
द्वारा: Kohoutek Jiri, और अन्य
प्रकाशित: (2012-04-01)