Cyclin-Dependent Kinase 12 (CDK12), Human Kinase Domain; A Target Enabling Package
A description of the materials and methods is included within the TEP datasheet. Cyclin-dependent kinase 12 (CDK12) phosphorylates RNA Pol II C-terminal domain (CTD) to promote transcriptional elongation of large DNA damage response genes. CDK12 is frequently mutated or amplified in cancer and its l...
| 其他作者: | |
|---|---|
| 格式: | Dataset |
| 出版: |
University of Oxford
2018
|
| 主题: |