Fluctuations in T cell receptor and pMHC interactions regulate T cell activation

Adaptive immune responses depend on interactions between T cell receptors (TCRs) and peptide major histocompatibility complex (pMHC) ligands located on the surface of T cells and antigen presenting cells (APCs), respectively. As TCRs and pMHCs are often only present at low copy numbers their interac...

Description complète

Détails bibliographiques
Auteurs principaux: Egan, JR, Abu-Shah, E, Dushek, O, Elliott, T, MacArthur, BD
Format: Journal article
Langue:English
Publié: The Royal Society 2022