Therapeutic monoclonal antibodies for Ebola virus infection derived from vaccinated humans

We describe therapeutic monoclonal antibodies isolated from human volunteers vaccinated with recombinant adenovirus expressing Ebola virus glycoprotein (EBOV GP) and boosted with modified vaccinia virus Ankara. Among 82 antibodies isolated from peripheral blood B cells, almost half neutralized GP ps...

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Bibliographic Details
Main Authors: Rijal, P, Elias, SC, Machado, SR, Xiao, J, Schimanski, L, O'Dowd, V, Baker, T, Barry, E, Mendelsohn, SC, Cherry, CJ, Jin, J, Labbé, GM, Donnellan, FR, Rampling, T, Dowall, S, Rayner, E, Findlay-Wilson, S, Carroll, M, Guo, J, Xu, X-N, Huang, K-YA, Takada, A, Burgess, G, McMillan, D, Popplewell, A, Lightwood, DJ, Draper, SJ, Townsend, AR
Format: Journal article
Language:English
Published: Cell Press 2019