Activation of autophagy ameliorates cardiomyopathy in Mybpc3-targeted knockin mice

<h4>Background</h4> <p>Alterations in autophagy have been reported in hypertrophic cardiomyopathy (HCM) caused by Danon disease, Vici syndrome, or LEOPARD syndrome, but not in HCM caused by mutations in genes encoding sarcomeric proteins, which account for most of HCM cases. MYBPC...

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Main Authors: Singh, SR, Zech, ATL, Geertz, B, Reischmann-Düsener, S, Osinska, H, Prondzynski, M, Krämer, E, Meng, Q, Redwood, C, van der Velden, J, Robbins, J, Schlossarek, S, Carrier, L
Format: Journal article
Language:English
Published: American Heart Association 2017