TARGET-Seq: a protocol for high-sensitivity single-cell mutational analysis and parallel RNA sequencing

Single-cell RNA-sequencing technologies are ideally placed to resolve intratumoral heterogeneity. However, the lack of coverage across key mutation hotspots has precluded the correlation of genetic and transcriptional readouts from the same single cell. To overcome this, we developed TARGET-seq, a p...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Rodriguez-Meira, A, O'Sullivan, J, Rahman, H, Mead, AJ
Format: Journal article
Język:English
Wydane: Cell Press 2020