Altered peptide ligands induce quantitatively but not qualitatively different intracellular signals in primary thymocytes.
Interaction of the T cell receptor (TCR) with peptide/major histocompatibility complexes (MHC) in the thymus is of critical importance for developing thymocytes. In a previous study, we described an antagonist peptide that inhibited negative selection of transgenic thymocytes induced by an agonist p...
Main Authors: | , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
1998
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