A novel machine learning based framework for developing composite digital biomarkers of disease progression

Background: Current methods of measuring disease progression of neurodegenerative disorders, including Parkinson's disease (PD), largely rely on composite clinical rating scales, which are prone to subjective biases and lack the sensitivity to detect progression signals in a timely manner. Digi...

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Bibliographic Details
Main Authors: Zhai, S, Liaw, A, Shen, J, Xu, Y, Svetnik, V, FitzGerald, JJ, Antoniades, CA, Holder, D, Dockendorf, MF, Ren, J, Baumgartner, R
Format: Journal article
Language:English
Published: Frontiers Media 2025