Multi-site clonality analysis uncovers pervasive heterogeneity across melanoma metastases

Multi-site clonality analysis uncovers pervasive heterogeneity across melanoma metastases

Metastatic melanoma carries a poor prognosis despite modern systemic therapies. Understanding the evolution of the disease could help inform patient management. Through whole-genome sequencing of 13 melanoma metastases sampled at autopsy from a treatment naïve patient and by leveraging the...

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Bibliographic Details
Main Authors:	Rabbie, R, Ansari-Pour, N, Cast, O, Lau, D, Scott, F, Welsh, SJ, Parkinson, C, Khoja, L, Moore, L, Tullett, M, Wong, K, Ferreira, I, Gómez, JMM, Levesque, M, Gallagher, FA, Jiménez-Sánchez, A, Riva, L, Miller, ML, Allinson, K, Campbell, PJ, Corrie, P, Wedge, DC, Adams, DJ
Format:	Journal article
Language:	English
Published:	Nature 2020

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