Pharmacokinetic-pharmacodynamic assessment of the hepatic and bone-marrow toxicities of the new trypanoside fexinidazole

Fexinidazole is a novel oral treatment for human African trypanosomiasis caused by Trypanosoma brucei gambiense (g-HAT). Fexinidazole also has activity against T. cruzi, the causative agent of Chagas disease. During the course of a dose ranging assessment in patients with chronic indeterminate Chaga...

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Bibliographic Details
Main Authors: Watson, J, Strub-Wourgraft, N, Tarral, A, Ribeiro, I, Tarning, J, White, N
Format: Journal article
Published: American Society for Microbiology 2019