Twofold radical-based synthesis of N,C-difunctionalized bicyclo[1.1.1]pentanes

<p>Bicyclo[1.1.1]pentylamines (BCPAs) are of growing importance to the pharmaceutical industry as sp<sup>3</sup>-rich bioisosteres of anilines and&nbsp;<em>N</em>-<em>tert</em>-butyl groups. Here we report a facile synthesis of 1,3-disubstituted BCPAs us...

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Váldodahkkit: Pickford, HD, Nugent, J, Owen, B, Mousseau, JJ, Smith, RC, Anderson, EA
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: American Chemical Society 2021