NF-κB suppression by the deubiquitinating enzyme cezanne: A novel negative feedback loop in pro-inflammatory signaling
Transcription factors belonging to the NF-κB family regulate inflammation by inducing pro-inflammatory molecules (e.g. interleukin (IL)-8) in response to cytokines (e.g. tumor necrosis factor (TNF) α, IL-1) or other stimuli. Several negative regulators of NF-κB, including the ubiquitin-editing enzym...
Main Authors: | , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2008
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