The role of B27 heavy chain dimer immune receptor interactions in spondyloarthritis.
HLA-B27 (B27) is strongly associated with spondyloarthopathy. The classical role of B27 is to present peptides from intracellular pathogens as a heterotrimeric complex with beta2 microglobulin for recognition by the T-cell receptor (TCR) of CD8 T-cells. In addition to heterotrimers, B27 can also be...
| Autores principales: | , |
|---|---|
| Formato: | Journal article |
| Lenguaje: | English |
| Publicado: |
2009
|