The robustness of proofreading to crowding-induced pseudo-processivity in the MAPK pathway
Double phosphorylation of protein kinases is a common feature of signalling cascades. This motif may reduce cross-talk between signalling pathways, as the second phosphorylation site allows for proofreading, especially when phosphorylation is distributive rather than processive. Recent studies sugge...
Main Authors: | , |
---|---|
Format: | Journal article |
Published: |
2014
|