The robustness of proofreading to crowding-induced pseudo-processivity in the MAPK pathway
Double phosphorylation of protein kinases is a common feature of signalling cascades. This motif may reduce cross-talk between signalling pathways, as the second phosphorylation site allows for proofreading, especially when phosphorylation is distributive rather than processive. Recent studies sugge...
Main Authors: | Ouldridge, T, Wolde, P |
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Format: | Journal article |
Published: |
2014
|
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