The pore structure and gating mechanism of K2P channels

Two-pore domain (K2P) potassium channels are important regulators of cellular electrical excitability. However, the structure of these channels and their gating mechanism, in particular the role of the bundle-crossing gate, are not well understood. Here, we report that quaternary ammonium (QA) ions...

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Bibliographic Details
Main Authors: Piechotta, P, Rapedius, M, Stansfeld, P, Bollepalli, M, Erhlich, G, Andres-Enguix, I, Fritzenschaft, H, Decher, N, Sansom, M, Tucker, S, Baukrowitz, T
Format: Journal article
Language:English
Published: 2011