Characterisation of the mitochondrial RNase P complex and associated diseases

<p>Human mitochondrial RNase P protein 1 (MRPP1) and 2 (MRPP2) form a methyltransferase complex with N1-methylation activity towards purine-9 on mitochondrial tRNA. A third component, mitochondrial RNase P protein 3 (MRPP3), adds RNase P 5'-end ribonuclease processing activity to the comp...

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Bibliographic Details
Main Author: Oerum, S
Other Authors: Yue, W
Format: Thesis
Published: 2016