General lessons from large-scale studies to identify human cancer predisposition genes.
There are now about 100 genes known to cause Mendelian inherited cancer syndromes, but these only explain a minor part of the familial clustering of the common cancers. The increased familial relative risk of cancer in the general population must largely involve genes of low- or moderate-penetrance....
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2010
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