General lessons from large-scale studies to identify human cancer predisposition genes.

There are now about 100 genes known to cause Mendelian inherited cancer syndromes, but these only explain a minor part of the familial clustering of the common cancers. The increased familial relative risk of cancer in the general population must largely involve genes of low- or moderate-penetrance....

Полное описание

Библиографические подробности
Главные авторы: Cazier, J, Tomlinson, I
Формат: Journal article
Язык:English
Опубликовано: 2010