Calorimetric dissection of colicin DNase--immunity protein complex specificity.

Calorimetric dissection of colicin DNase--immunity protein complex specificity.

We explore the thermodynamic strategies used to achieve specific, high-affinity binding within a family of conserved protein-protein complexes. Protein-protein interactions are often stabilized by a conserved interfacial hotspot that serves as the anchor for the complex, with neighboring variable re...

Detaylı Bibliyografya
Asıl Yazarlar:	Keeble, A, Kirkpatrick, N, Shimizu, S, Kleanthous, K
Materyal Türü:	Journal article
Dil:	English
Baskı/Yayın Bilgisi:	2006

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