A SNP in the ACT gene associated with astrocytosis and rapid cognitive decline in AD.

There is biochemical and animal model evidence supporting a pathological role of the ACT gene in AD. However, direct genetic evidence remains controversial and has been mostly limited to individual single nucleotide polymorphism (SNP) analysis. To resolve this apparent conflict we have used a high-d...

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Bibliographic Details
Main Authors: Belbin, O, Dunn, J, Chappell, S, Ritchie, A, Ling, Y, Morgan, L, Pritchard, A, Warden, DR, Lendon, C, Lehmann, D, Mann, D, Smith, A, Kalsheker, N, Morgan, K
Format: Journal article
Language:English
Published: 2008