A SNP in the ACT gene associated with astrocytosis and rapid cognitive decline in AD.

A SNP in the ACT gene associated with astrocytosis and rapid cognitive decline in AD.

There is biochemical and animal model evidence supporting a pathological role of the ACT gene in AD. However, direct genetic evidence remains controversial and has been mostly limited to individual single nucleotide polymorphism (SNP) analysis. To resolve this apparent conflict we have used a high-d...

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Detalhes bibliográficos
Principais autores: Belbin, O, Dunn, J, Chappell, S, Ritchie, A, Ling, Y, Morgan, L, Pritchard, A, Warden, DR, Lendon, C, Lehmann, D, Mann, D, Smith, A, Kalsheker, N, Morgan, K
Formato: Journal article
Idioma:English
Publicado em: 2008

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