Satb2 is a postmitotic determinant for upper-layer neuron specification in the neocortex.

Pyramidal neurons of the neocortex can be subdivided into two major groups: deep- (DL) and upper-layer (UL) neurons. Here we report that the expression of the AT-rich DNA-binding protein Satb2 defines two subclasses of UL neurons: UL1 (Satb2 positive) and UL2 (Satb2 negative). In the absence of Satb...

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Bibliographic Details
Main Authors: Britanova, O, de Juan Romero, C, Cheung, A, Kwan, K, Schwark, M, Gyorgy, A, Vogel, T, Akopov, S, Mitkovski, M, Agoston, D, Sestan, N, Molnár, Z, Tarabykin, V
Format: Journal article
Language:English
Published: 2008