Safety and immunogenicity of a virus-like particle pandemic influenza A (H1N1) 2009 vaccine: results from a double-blinded, randomized Phase I clinical trial in healthy Asian volunteers.

METHODS: A novel, fully bacterially produced recombinant virus-like particle (VLP) based influenza vaccine (gH1-Qbeta) against A/California/07/2009(H1N1) was tested in a double-blind, randomized phase I clinical trial at two clinical sites in Singapore. The trial evaluated the immunogenicity and saf...

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Bibliographic Details
Main Authors: Low, J, Lee, L, Ooi, E, Ethirajulu, K, Yeo, P, Matter, A, Connolly, J, Skibinski, D, Saudan, P, Bachmann, M, Hanson, B, Lu, Q, Maurer-Stroh, S, Lim, S, Novotny-Diermayr, V
Format: Journal article
Language:English
Published: 2014