A new model for CD8+ T cell memory inflation based upon a recombinant adenoviral vector.

CD8(+) T cell memory inflation, first described in murine CMV (MCMV) infection, is characterized by the accumulation of high-frequency, functional Ag-specific CD8(+) T cell pools with an effector-memory phenotype and enrichment in peripheral organs. Although persistence of Ag is considered essential...

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Bibliographic Details
Main Authors: Bolinger, B, Sims, S, O'Hara, G, de Lara, C, Tchilian, E, Firner, S, Engeler, D, Ludewig, B, Klenerman, P
Format: Journal article
Language:English
Published: 2013