Epithelial cells bearing class II molecules stimulate allogeneic human colonic intraepithelial lymphocytes.

HLA-DR+ gut epithelial cells may present antigen to intraepithelial lymphocytes (IEL). This study aimed to isolate an IEL population from the human colon to activate CD3 + IEL by a human colonic epithelial cell line (HT-29), bearing different concentrations of class II antigen (HLA-DR). IEL were iso...

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Bibliographic Details
Main Authors: Hoang, P, Crotty, B, Dalton, H, Jewell, D
Format: Journal article
Language:English
Published: BMJ Publishing Group 1992