A molecular assembly system that renders antigens of choice highly repetitive for induction of protective B cell responses.
Virus like particles (VLPs) are known to induce potent B cell responses in the absence of adjuvants. Moreover, epitope-specific antibody responses may be induced by VLPs that contain peptides inserted in their immunodominant regions. However, due to steric problems, the size of the peptides capable...
Main Authors: | , , , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2002
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