XPF protein levels determine sensitivity of malignant melanoma cells to oxaliplatin chemotherapy: Suitability as a biomarker for patient selection

As the options for systemic treatment of malignant melanoma (MM) increase, the need to develop biomarkers to identify patients who might benefit from cytotoxic chemotherapy becomes more apparent. In preclinical models, oxaliplatin has activity in cisplatin-resistant cells. In this study, we have sho...

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Bibliographic Details
Main Authors: Hatch, S, Swift, L, Caporali, S, Carter, R, Hill, E, Macgregor, T, D'Atri, S, Middleton, M, McHugh, P, Sharma, R
Format: Journal article
Published: 2014