The role of fibroblast ENPP1 expression on anti-tumour immunity
<p><strong>Background:</strong> <p>Highly chromosomally unstable (CIN-high) tumours such as oesophageal adenocarcinoma (OAC) chronically activate the cGAS-STING pathway to produce immunostimulatory 2’3’- cGAMP. This cyclic dinucleotide is exported from tumour cells and can in...
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| Format: | Thesis |
| Language: | English |
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2023
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