Longitudinal genomic surveillance of Plasmodium falciparum malaria parasites reveals complex genomic architecture of emerging artemisinin resistance in western Thailand

<strong>Background</strong> Artemisinin-based combination therapies are the first line of treatment for Plasmodium falciparum infections worldwide, but artemisinin resistance has risen rapidly in Southeast Asia over the last decade. Mutations in the kelch13 gene have been implicated in t...

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Detalhes bibliográficos
Main Authors: Cerqueira, G, Cheeseman, I, Schaffner, S, Nair, S, McDew-White, M, Phyo, A, Ashley, E, Melnikov, A, Rogov, P, Birren, B, Nosten, F, Anderson, T, Neafsey, D
Formato: Journal article
Publicado em: BioMed Central 2017