Allograft rejection mediated by memory T cells is resistant to regulation.

Alloreactive memory T cells may be refractory to many of the tolerance-inducing strategies that are effective against naive T cells and thus present a significant barrier to long-term allograft survival. Because CD4(+)CD25(+) regulatory T cells (Tregs) are critical elements of many approaches to suc...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, J, Brook, M, Carvalho-Gaspar, M, Zhang, J, Ramon, H, Sayegh, M, Wood, K, Turka, L, Jones, N
Formato: Journal article
Lenguaje:English
Publicado: 2007