Allograft rejection mediated by memory T cells is resistant to regulation.
Alloreactive memory T cells may be refractory to many of the tolerance-inducing strategies that are effective against naive T cells and thus present a significant barrier to long-term allograft survival. Because CD4(+)CD25(+) regulatory T cells (Tregs) are critical elements of many approaches to suc...
Hoofdauteurs: | Yang, J, Brook, M, Carvalho-Gaspar, M, Zhang, J, Ramon, H, Sayegh, M, Wood, K, Turka, L, Jones, N |
---|---|
Formaat: | Journal article |
Taal: | English |
Gepubliceerd in: |
2007
|
Gelijkaardige items
-
Regulatory T cells can prevent memory CD8+ T-cell-mediated rejection following polymorphonuclear cell depletion.
door: Jones, N, et al.
Gepubliceerd in: (2010) -
The impact of memory T cells on rejection and the induction of tolerance.
door: Brook, M, et al.
Gepubliceerd in: (2006) -
Location and time-dependent control of rejection by regulatory T cells culminates in a failure to generate memory T cells.
door: Carvalho-Gaspar, M, et al.
Gepubliceerd in: (2008) -
Differential susceptibility of heart, skin, and islet allografts to T cell-mediated rejection.
door: Jones, N, et al.
Gepubliceerd in: (2001) -
Chemokine gene expression during allograft rejection: comparison of two quantitative PCR techniques.
door: Carvalho-Gaspar, M, et al.
Gepubliceerd in: (2005)