Direct radiolabelling of proteins at cysteine using [18F]-fluorosugars.

A strategy for the site-specific attachment of 2-deoxy-2-fluorosugars to cysteine and dehydroalanine tagged proteins is reported. When combined with thionation of fluorosugars, such as the widely available (18)F probe 2-deoxy-2-[(18)F]fluoroglucose ([(18)F]FDG), this methodology allows fast and dire...

Full description

Bibliographic Details
Main Authors: Boutureira, O, Bernardes, G, D'Hooge, F, Davis, B
Format: Journal article
Language:English
Published: 2011