Direct radiolabelling of proteins at cysteine using [18F]-fluorosugars.
A strategy for the site-specific attachment of 2-deoxy-2-fluorosugars to cysteine and dehydroalanine tagged proteins is reported. When combined with thionation of fluorosugars, such as the widely available (18)F probe 2-deoxy-2-[(18)F]fluoroglucose ([(18)F]FDG), this methodology allows fast and dire...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
2011
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