Limitations of the anti-idiotype strategy for an HIV vaccine.

Attempts to raise protective immunity to HIV have been notably ineffective. However the conservation of binding of different virus strains to CD4 suggests that the HIV envelope glycoprotein (gp120) should have a conserved site for CD4. Attempts to raise neutralizing anti-idiotypes to CD4 monoclonal...

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Bibliographic Details
Main Authors: Beverley, P, Healey, D, Broadhurst, K, Sattentau, Q
Format: Journal article
Language:English
Published: 1989