Mannuronolactone acetonide: easy access to C-3 OH and C-5 OH of mannose

The synthesis of D-mannuronolactone acetonide 1 is described from alginic acid and provides an efficient route for the manipulation at C-5 of mannose. Reduction gives a new acetonide of mannose, 1,2-O-isopropylidene-β-D-mannofuranose which, on further acetonation, gives 1,2:5,6-di-O-isopropylidene-β...

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Bibliographic Details
Main Authors: Watterson, M, Martin, A, Krulle, T, Estevez, J, Fleet, G
Format: Journal article
Language:English
Published: 1997