Integrating models to quantify environment mediated drug resistance

Drug resistance is the single most important driver of cancer treatment failure for modern targeted therapies, and the dialogue between tumor and stroma has been shown to modulate the response to molecularly targeted therapies through proliferative and survival signaling. In this work, we investigat...

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Bibliographic Details
Main Authors: Picco, N, Sahai, E, Maini, P, Anderson, A
Format: Journal article
Published: American Association for Cancer Research 2017