New strategies for targeting the hypoxic tumour microenvironment in breast cancer

Radiation and drug resistance remain major challenges and causes of mortality in the treatment of locally advanced, recurrent and metastatic breast cancer. Metabolic reprogramming is a recently recognised hallmark of cancer with the hypoxic acidic extracellular environment as a major driver of invas...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Ward, C, Langdon, S, Mullen, P, Harris, A, Harrison, D, Supuran, C, Kunkler, I
Format: Journal article
Sprache:English
Veröffentlicht: 2013