Dissecting the self-assembly kinetics of multimeric pore-forming toxins.

Pore-forming toxins are ubiquitous cytotoxins that are exploited by both bacteria and the immune response of eukaryotes. These toxins kill cells by assembling large multimeric pores on the cell membrane. However, a quantitative understanding of the mechanism and kinetics of this self-assembly proces...

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Bibliographic Details
Main Authors: Lee, A, Senior, M, Wallace, M, Woolley, T, Griffiths, I
Format: Journal article
Language:English
Published: Royal Society 2016