Quantifying the heterogeneity of macromolecular machines by mass photometry

Sample purity is central to in vitro studies of protein function and regulation, and to the efficiency and success of structural studies using techniques such as x-ray crystallography and cryo-electron microscopy (cryo-EM). Here, we show that mass photometry (MP) can accurately characterize the hete...

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Bibliographic Details
Main Authors: Sonn-Segev, A, Belacic, K, Bodrug, T, Young, G, VanderLinden, RT, Schulman, BA, Schimpf, J, Friedrich, T, Dip, PV, Schwartz, TU, Bauer, B, Peters, J-M, Benesch, JLP, Struwe, WB, Brown, NG, Haselbach, D, Kukura, P
Format: Journal article
Language:English
Published: Springer Nature 2020
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