Quantifying the heterogeneity of macromolecular machines by mass photometry
Sample purity is central to in vitro studies of protein function and regulation, and to the efficiency and success of structural studies using techniques such as x-ray crystallography and cryo-electron microscopy (cryo-EM). Here, we show that mass photometry (MP) can accurately characterize the hete...
Үндсэн зохиолчид: | Sonn-Segev, A, Belacic, K, Bodrug, T, Young, G, VanderLinden, RT, Schulman, BA, Schimpf, J, Friedrich, T, Dip, PV, Schwartz, TU, Bauer, B, Peters, J-M, Benesch, JLP, Struwe, WB, Brown, NG, Haselbach, D, Kukura, P |
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Формат: | Journal article |
Хэл сонгох: | English |
Хэвлэсэн: |
Springer Nature
2020
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Нөхцлүүд: |
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