Intramuscular artemether vs intravenous quinine: an open, randomized trial in Malawian children with cerebral malaria.

Intramuscular artemether vs intravenous quinine: an open, randomized trial in Malawian children with cerebral malaria.

OBJECTIVES: To compare artemether (by intramuscular injection) and quinine (by intravenous infusion) as treatments for cerebral malaria in African children. METHODS: An open, randomized trial conducted at the Queen Elizabeth Central Hospital in Blantyre, Malawi. This trial was part of a multicentre...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Taylor, T, Wills, B, Courval, J, Molyneux, M
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	1998

Eitemau Tebyg

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gan: Taylor, T, et al.
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gan: Taylor, T, et al.
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gan: White, N
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gan: Waller, D, et al.
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Quinine pharmacokinetics and toxicity in cerebral and uncomplicated Falciparum malaria.
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