Two for tau: automated model discovery reveals two-stage tau aggregation dynamics in Alzheimer’s disease

Alzheimer’s disease is a neurodegenerative disorder characterized by the presence of amyloid-𝛽 plaques and the accumulation of misfolded tau proteins and neurofibrillary tangles in the brain. A thorough understanding of the local accumulation of tau is critical to develop effective therapeutic strat...

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Bibliographic Details
Main Authors: Stockman, CA, Goriely, A, Kuhl, E, Jerusalem, A, Alzheimer’s Disease Neuroimaging Initiative
Format: Journal article
Language:English
Published: Elsevier 2024