Two for tau: automated model discovery reveals two-stage tau aggregation dynamics in Alzheimer’s disease
Alzheimer’s disease is a neurodegenerative disorder characterized by the presence of amyloid-𝛽 plaques and the accumulation of misfolded tau proteins and neurofibrillary tangles in the brain. A thorough understanding of the local accumulation of tau is critical to develop effective therapeutic strat...
Main Authors: | , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Elsevier
2024
|