Photoaffinity labelling displacement assay using multiple recombinant protein domains

The development and optimisation of a photoaffinity labelling (PAL) displacement assay is presented, where a highly efficient PAL probe was used to report on the relative binding affinities of compounds to specific binding sites in multiple recombinant protein domains in tandem. The N- and C-termina...

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Bibliographic Details
Main Authors: Fallon, DJ, Phillipou, A, Schofield, CJ, House, D, Tomkinson, NCO, Bush, JT
Format: Journal article
Language:English
Published: Portland Press 2023